Question 1:
What are the chemical modifications that can occur on DNA molecules to regulate gene expression?
Explanation: C) Methylation is a chemical modification that can occur on DNA molecules to regulate gene expression. Methylation typically involves the addition of a methyl group to cytosine residues and can influence gene silencing.
Question 2:
Which of the following is an example of an epigenetic modification?
Explanation: D) DNA methylation is an example of an epigenetic modification. It involves the addition of a methyl group to DNA and can lead to changes in gene expression patterns without altering the DNA sequence itself.
Question 3:
What is the role of histone acetylation in gene expression?
Explanation: C) Histone acetylation plays a role in gene activation. Acetylation of histone proteins neutralizes their positive charge, leading to a more open chromatin structure and increased accessibility of the DNA, facilitating gene expression.
Question 4:
What is the function of microRNAs (miRNAs) in gene regulation?
Explanation: D) MicroRNAs (miRNAs) function in post-transcriptional regulation. They can bind to complementary sequences in mRNA molecules, leading to mRNA degradation or inhibition of translation, thereby controlling gene expression.
Question 5:
What is the term for the modification of histones that promotes a compacted chromatin structure and gene silencing?
Explanation: A) Methylation of histones promotes a compacted chromatin structure and gene silencing. Methylation can lead to the recruitment of proteins that maintain a repressive chromatin state, inhibiting gene expression.
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